Genzyme Ireland Ltd.

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Genzyme Corporation is a biotechnology company that develops and markets innovative products and services for unmet medical needs. With three divisions, each targeting a specific area of expertise, Genzyme Corporation combines the resources and strengths of one of the world's largest biotechnology companies with the entrepreneurial spirit and dedication of focused, flexible, and independent businesses. Genzyme uses a wide range of technologies in its research and development efforts. With a strong international infrastructure, including extensive capabilities in sales and marketing, manufacturing, and regulatory affairs, Genzyme has a successful track record in working closely with patients and physicians.

IDA Industrial Park, Old Kilmeaden Road, Waterford, Co. Waterford
Fax:353 (0) 51 594105

Genzyme announced on May 29 2001 that it will establish a manufacturing facility in the Republic of Ireland initially for the production of RenagelĀ® (sevelamer hydrochloride), a phosphate binder for dialysis patients that is the company's fastest growing product. Specifically, Genzyme has purchased an existing 120,000 square foot facility located on a 32-acre site in the city of Waterford that will be converted for use in manufacturing the tablet formulation of Renagel. Genzyme expects that the facility will be fully operational and approved by regulatory authorities by the middle of 2003.

As a follow on to the establishment of the Renagel tableting facility, Genzyme is developing a plan for a multi-product manufacturing center in Waterford. This center will include a biologics fill and finishing plant that would support future protein and antibody products manufactured at other Genzyme facilities, as well as a bulk pharmaceutical manufacturing facility for polymers and small molecules.